Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 5-bromofuran-2-carboxylate

  • CAS No. 2527-99-3

  • Cat. No. CS-W002362
  • Purity≥95%
  • MDL No.MFCD00092313

*For research and further manufacturing use only, not for direct human use.

Methyl 5-bromofuran-2-carboxylate|CS-W002362

Structure of 2527-99-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 2527-99-3
  • Cat. No. CS-W002362
  • Purity ≥95%
  • MDL No. MFCD00092313
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BrO₃
  • Molecular Weight 205.01
  • Synonym(s) Methyl 5-Bromo-2-furoate; Methyl 5-bromofuran-2-carboxylate
  • SMILES COC(=O)c1ccc(o1)Br

Description

Methyl 5-bromofuran-2-carboxylate is a bench-stable, moisture-tolerant heterocyclic ester featuring a bromine substituent at the 5-position of the furan ring. This electron-deficient scaffold integrates readily into transition-metal-catalyzed cross-coupling reactions, enabling efficient access to functionalized furan derivatives for medicinal chemistry and materials science applications.

Application

Methyl 5-bromofuran-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo substituent. The furan ring provides a platform for electrophilic functionalization and further derivatization, while the ester group offers compatibility with standard reduction and nucleophilic substitution protocols. Its bench-stable nature and predictable reactivity make it suitable for iterative synthetic sequences in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      74-88-4
    • ~81%
    • In-stock
      Methyl 5-bromofuran-2-carboxylate|CS-W002362
      2527-99-3

    References

    • AMEDIS PHARMACEUTICALS LTD. Patent: WO2004/45625 A1, 2004 ; Location in patent: Page/Page column 18,19 ;
  • Route2
    • null|null
      67-56-1
    • In-stock
      5-Bromofuroic acid|CS-W001115
      585-70-6
    • ~97%
    • In-stock
      Methyl 5-bromofuran-2-carboxylate|CS-W002362
      2527-99-3

    References

    • Linshoeft, Julian; Heinrich, Annika C. J.; Segler, Stephan A. W.; Gates, Paul J.; Staubitz, Anne Organic Letters, 2012 , vol. 14, # 22 p. 5644 - 5647
  • Route3

    References

    • Tetrahedron, , vol. 39, # 15 p. 2531 - 2549

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   39.44
  • LogP   1.8287
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Methyl 5-bromofuran-2-carboxylate sigmaMethyl 5-bromofuran-2-carboxylate manufacturerMethyl 5-bromofuran-2-carboxylate priceMethyl 5-bromofuran-2-carboxylate structureMethyl 5-bromofuran-2-carboxylate SDSbuy Methyl 5-bromofuran-2-carboxylateMethyl 5-bromofuran-2-carboxylate supplierMethyl 5-bromofuran-2-carboxylate usesMethyl 5-bromofuran-2-carboxylate molecular weightprice of Methyl 5-bromofuran-2-carboxylateMethyl 5-bromofuran-2-carboxylate chemical name formula of Methyl 5-bromofuran-2-carboxylate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label