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CS-W001157 4
Total: USD 88.00

1-Methoxynaphthalene-2-boronic acid

  • CAS No. 252670-79-4

  • Cat. No. CS-0098532
  • Purity≥99%
  • MDL No.MFCD18412861

*For research and further manufacturing use only, not for direct human use.

1-Methoxynaphthalene-2-boronic acid|CS-0098532

Structure of 252670-79-4

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General Information

  • CAS No. 252670-79-4
  • Cat. No. CS-0098532
  • Purity ≥99%
  • MDL No. MFCD18412861
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁BO₃
  • Molecular Weight 202.01
  • Synonym(s) None
  • SMILES OB(C1=CC=C2C=CC=CC2=C1OC)O

Description

1-Methoxynaphthalene-2-boronic acid features a boronic acid group fused to a methoxynaphthalene scaffold, delivering enhanced stability and solubility in polar organic media. This bench-stable reagent enables efficient Suzuki-Miyaura coupling under mild conditions, facilitating the construction of complex biaryl architectures with high functional group tolerance.

Application

1-Methoxynaphthalene-2-boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. Its methoxy-substituted naphthalene core offers enhanced stability and solubility compared to unsubstituted analogs, while the boronic acid functionality facilitates reliable coupling under mild conditions. The compound exhibits excellent bench stability and is readily purified by recrystallization or flash chromatography, making it well-suited for both academic and industrial R&D workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   0.5282
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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