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Structure of 25247-28-3
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4-Methylpyridazine-3-carboxylic acid features a conjugated pyridazine core bearing a methyl group at the 4-position and a carboxylic acid at the 3-position, delivering enhanced solubility and stability under standard conditions. This scaffold integrates readily into bioactive molecule design, particularly in kinase inhibitor and pharmaceutical lead development, where its electron-deficient heterocycle supports targeted interactions.
4-Methylpyridazine-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds through standard coupling and functional group transformation protocols. Its dual functionality—electron-deficient pyridazine core and carboxylic acid group—facilitates conjugation via amide bond formation and supports metal-catalyzed cross-coupling reactions. The methyl substituent enhances metabolic stability and modulates electronic properties, while the compound exhibits good bench stability and ease of purification, making it well-suited for high-throughput library synthesis and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: