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CS-W001157 4
Total: USD 88.00

3-(3,4,5-Trimethoxyphenyl)propanoic acid

  • CAS No. 25173-72-2

  • Cat. No. CS-0041622
  • Purity≥98%
  • MDL No.MFCD00002775
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-(3,4,5-Trimethoxyphenyl)propanoic acid|CS-0041622

Structure of 25173-72-2

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Description

This 3-(3,4,5-trimethoxyphenyl)propanoic acid features a highly electron-rich aromatic core flanked by a flexible propanoic acid chain. The three methoxy groups enhance solubility and stability under standard conditions. This structure enables efficient coupling in synthetic workflows, particularly useful in medicinal chemistry for constructing bioactive scaffolds with improved metabolic resistance.

Application

3-(3,4,5-Trimethoxyphenyl)propanoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive compounds through established coupling and functionalization protocols. Its aromatic core with three methoxy groups enhances solubility and metabolic stability, while the carboxylic acid functionality facilitates direct derivatization via amide, ester, or acyl transfer reactions. The compound exhibits excellent bench stability and is compatible with standard purification methods, making it ideal for high-throughput screening campaigns and API intermediate development.

General Information

  • CAS No. 25173-72-2
  • Cat. No. CS-0041622
  • Purity ≥98%
  • MDL No. MFCD00002775
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆O₅
  • Molecular Weight 240.25
  • Synonym(s) None
  • SMILES O=C(O)CCC1=CC(OC)=C(OC)C(OC)=C1

Computational Chemistry Data

  • TPSA   64.99
  • LogP   1.7296
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   6

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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