DMT-2'-O-MOE-rA(Bz) phosphoramidite

Name: DMT-2'-O-MOE-rA(Bz) phosphoramidite
Brand: ChemScene
Availability: InStock
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CAS No. 251647-53-7
Cat. No. CS-0023727
Purity≥97%
MDL No.MFCD29472587

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

DMT-2'-O-MOE-rA(Bz) phosphoramidite|CS-0023727

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Description

Molybdenum(IV) selenide is used in transistors and photodetectors. It is also used as a solid lubricant. Further, it is used in piezoelectric and solar cells.

Application

DMT-2'-O-MOE-rA(Bz) phosphoramidite serves as a key building block for the synthesis of modified oligonucleotides, enabling site-specific incorporation of 2'-O-methoxyethyl (MOE) ribose modifications. The protected adenine base (Bz) ensures orthogonal compatibility during solid-phase synthesis, while the dimethoxytrityl (DMT) group provides efficient monitoring and purification via chromatographic separation. This reagent exhibits excellent stability, high coupling efficiency, and compatibility with standard desalting and HPLC purification protocols, making it ideal for applications requiring enhanced nuclease resistance and binding affinity in antisense and RNA therapeutics.

General Information

CAS No. 251647-53-7
Cat. No. CS-0023727
Purity ≥97%
MDL No. MFCD29472587
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅₀H₅₈N₇O₉P
Molecular Weight 932.01
Synonym(s) None
SMILES O=C(C1=CC=CC=C1)NC2=NC=NC3=C2N=CN3[C@H]4[C@H](OCCOC)[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C5=CC=C(OC)C=C5)(C6=CC=CC=C6)C7=CC=C(OC)C=C7)O4

Computational Chemistry Data

TPSA 173.57
LogP 8.65218
H_Acceptors 15
H_Donors 1
Rotatable_Bonds 22

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic heterocycle compounds Purine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Nucleosides & Nucleotides 2'-O-MOE-phosphoramidite monomer

Chemical Biology Pharmaceutical Development and Drug Discovery Research Nucleic Acid Chemistry Nucleoside Phosphoramidites

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Nucleic Acid Chemistry Nucleoside Phosphoramidites

Chemical Biology Nucleic Acid Chemistry Methylated Nucleosides

Chemical Biology Nucleic Acid Chemistry Nucleoside Phosphoramidites

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DMT-2'-O-MOE-rA(Bz) phosphoramidite

CAS No. 251647-53-7

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