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CS-W001157 4
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(S)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride

  • CAS No. 2512230-61-2

  • Cat. No. CS-0698175
  • Molecule weight278.65
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride|CS-0698175

Structure of 2512230-61-2

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General Information

  • CAS No. 2512230-61-2
  • Cat. No. CS-0698175
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₂Cl₃N₃
  • Molecular Weight 278.65
  • Synonym(s) None
  • SMILES Cl.Cl.Cl.CN1CCN(CC1)[C@H]1CCNC1

Description

(S)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride is a chiral piperazine derivative featuring a pyrrolidin-3-yl substituent and a methyl group at the 1-position. This configuration enhances its solubility and bioavailability, making it valuable in medicinal chemistry for constructing CNS-targeted pharmacophores. The trihydrochloride salt form ensures excellent stability and handling under standard bench conditions.

Application

(S)-1-Methyl-4-(pyrrolidin-3-yl)piperazine trihydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the construction of complex nitrogen-containing scaffolds. Its trihydrochloride salt form enhances solubility and stability for solution-phase synthesis. The molecule functions as a privileged core in CNS-targeted compound libraries, offering favorable functional group tolerance and compatibility with standard coupling and reductive amination protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   18.51
  • LogP   0.8611
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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