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2-((4-Aminophenyl)sulfonyl)ethyl hydrogen sulfate

  • CAS No. 2494-89-5

  • Cat. No. CS-0186374
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-((4-Aminophenyl)sulfonyl)ethyl hydrogen sulfate|CS-0186374

Structure of 2494-89-5

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General Information

  • CAS No. 2494-89-5
  • Cat. No. CS-0186374
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO₆S₂
  • Molecular Weight 281.31
  • Synonym(s) Vinyl sulphone para base
  • SMILES C1=C(C=CC(=C1)S(=O)(=O)CCOS(=O)(=O)O)N

Description

This sulfonate ester features a 4-aminophenylsulfonyl group linked to an ethyl hydrogen sulfate moiety, enabling efficient conjugation in bioorthogonal labeling. The electron-rich aniline functionality enhances reactivity, while the sulfate ester provides a stable yet cleavable linker under physiological conditions.

Synthesis

  • Route1
    • null|null
      27375-52-6
    • ~94%
    • In-stock
      2-((4-Aminophenyl)sulfonyl)ethyl hydrogen sulfate|CS-0186374
      2494-89-5

    References

    • Sumitomo Chemical Company, Limited Patent: US4482501 A1, 1984 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   123.76
  • LogP   -0.1381
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   5

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