Lot numbers can be found on the outside label of a product:
Carbethoxymethyl cyclopropyl ketone
-
CAS No. 24922-02-9
- Cat. No. CS-W009178
- Purity≥96%
- MDL No.MFCD00184570
*For research and further manufacturing use only, not for direct human use.
Structure of 24922-02-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 24922-02-9
- Cat. No. CS-W009178
- Purity ≥96%
- MDL No. MFCD00184570
- Storage RT, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₁₂O₃
- Molecular Weight 156.18
- Synonym(s) Ethyl 3-cyclopropyl-3-oxopropanoate; Ethyl 3-cyclopropyl-3-oxopropionate; Ethyl β-cyclopropyl-β-ketopropionate; NSC 97121; β-Oxocyclopropanepropanoic acid ethyl ester
- SMILES O=C(CC(OCC)=O)C1CC1
Description
Carbethoxymethyl cyclopropyl ketone features a strained cyclopropyl ring fused to a ketone bearing a carbethoxy-methyl side chain. This arrangement imparts high reactivity for cycloaddition and nucleophilic functionalization, enabling efficient construction of complex heterocycles under mild conditions. The molecule exhibits excellent stability during storage and compatibility with common organic solvents.
Application
Carbethoxymethyl cyclopropyl ketone serves as a versatile synthon in heterocyclic synthesis, enabling efficient construction of substituted pyrrolidines and γ-lactams via Michael addition or cyclization cascades. Its cyclopropyl moiety imparts conformational rigidity, while the ester and ketone functionalities offer orthogonal reactivity for sequential transformations. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative medicinal chemistry campaigns and scalable process development.
Synthesis
-
Route1
-
In-stock
6148-64-7 -
4023-34-1 - ~93%
-
In-stock
24922-02-9
References
-
DAIICHI PHARMACEUTICAL CO., LTD. Patent: EP1479681 A1, 2004 ; Location in patent: Page 59 ;
-
-
Route2
-
765-43-5
- ~54%
-
450-95-3 -
In-stock
24922-02-9
References
-
E. R. Squibb and Sons, Inc. Patent: US5506219 A1, 1996 ; US 5506219 A
-
-
Route3
-
In-stock
1071-46-1 -
4023-34-1
- ~64%
-
In-stock
24922-02-9
References
-
J. Uriach and Cia, S.A. Patent: US5827863 A1, 1998 ; US 5827863 A
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 43.37
- LogP 0.9187
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 4
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Carbethoxymethyl cyclopropyl ketone sigmaCarbethoxymethyl cyclopropyl ketone manufacturerCarbethoxymethyl cyclopropyl ketone priceCarbethoxymethyl cyclopropyl ketone structureCarbethoxymethyl cyclopropyl ketone SDSbuy Carbethoxymethyl cyclopropyl ketoneCarbethoxymethyl cyclopropyl ketone supplierCarbethoxymethyl cyclopropyl ketone usesCarbethoxymethyl cyclopropyl ketone molecular weightprice of Carbethoxymethyl cyclopropyl ketoneCarbethoxymethyl cyclopropyl ketone chemical name formula of Carbethoxymethyl cyclopropyl ketone