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Ethyl (R)-3-hydroxybutyrate

  • CAS No. 24915-95-5

  • Cat. No. CS-D1461
  • Purity≥98%
  • MDL No.MFCD00075386

*For research and further manufacturing use only, not for direct human use.

Ethyl (R)-3-hydroxybutyrate|CS-D1461

Structure of 24915-95-5

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General Information

  • CAS No. 24915-95-5
  • Cat. No. CS-D1461
  • Purity ≥98%
  • MDL No. MFCD00075386
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂O₃
  • Molecular Weight 132.16
  • Synonym(s) Ethyl (R)-3-hydroxybutanoate
  • SMILES C[C@@H](O)CC(OCC)=O

Description

Ethyl (R)-3-hydroxybutyrate is a chiral ester featuring a stereodefined hydroxyl group at the C3 position, enabling precise incorporation into asymmetric synthesis. This bench-stable reagent facilitates the construction of enantiopure building blocks for pharmaceutical intermediates and natural product analogs, offering predictable stereochemical outcomes in nucleophilic transformations.

Synthesis

  • Route1

    References

    • Benincori; Piccolo; Rizzo; Sannicolo Journal of Organic Chemistry, 2000 , vol. 65, # 24 p. 8340 - 8347
  • Route2

    References

    • Bhalerao; Chandraprakash; Babu; Fadnavis Synthetic Communications, 1993 , vol. 23, # 9 p. 1201 - 1208
  • Route3
    • null|null
      1006696-12-3
    • ~94%
    • In-stock
      Ethyl (R)-3-hydroxybutyrate|CS-D1461
      24915-95-5

    References

    • Lee, Ji-Eon; Yun, Jaesook Angewandte Chemie - International Edition, 2008 , vol. 47, # 1 p. 145 - 147

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.3204
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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