1,4-Bis(dimethylsilyl)benzene

Name: 1,4-Bis(dimethylsilyl)benzene
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2488-01-9
Cat. No. CS-0006218
Purity≥98%
MDL No.MFCD00039790

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1,4-Bis(dimethylsilyl)benzene|CS-0006218

Structure of 2488-01-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 2488-01-9
Cat. No. CS-0006218
Purity ≥98%
MDL No. MFCD00039790
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₈Si₂
Molecular Weight 194.42
Synonym(s) 1,4-Phenylenebis(dimethylsilane)
SMILES C[SiH](C1=CC=C([SiH](C)C)C=C1)C

Description

1,4-Bis(dimethylsilyl)benzene features two dimethylsilyl groups at para positions on a benzene ring, delivering exceptional thermal and oxidative stability. This sterically shielded aryl scaffold enables reliable use in high-temperature synthetic transformations. The silyl moieties enhance solubility in nonpolar media and facilitate downstream functionalization via Si–C bond cleavage or transition-metal-catalyzed coupling reactions.

Application

1,4-Bis(dimethylsilyl)benzene serves as a robust silyl-protected aromatic building block, enabling selective functionalization at the para positions while maintaining stability under a range of reaction conditions. Its dual trimethylsilyl groups offer excellent protection against oxidation and nucleophilic attack, facilitating orthogonal transformations in complex molecule synthesis. The compound exhibits high bench stability, ease of purification, and compatibility with standard cross-coupling protocols, making it a valuable scaffold for the construction of substituted arenes and heterocyclic systems in medicinal chemistry and materials science.

Synthesis

Route1
- 1066-35-9
- In-stock
  
  106-37-6
- ~85%
- In-stock
  
  2488-01-9
References
- Plenio, Herbert Journal of Organometallic Chemistry, 1992 , vol. 435, # 1.2 p. 21 - 28
Route2
- 1066-35-9
- In-stock
  
  106-46-7
- ~86%
- In-stock
  
  2488-01-9
References
- Nguyen, Binh T. Patent: US2003/233005 A1, 2003 ; Location in patent: Page 3 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H227-H302
Precautionary Statements : P210-P264-P270-P280-P330-P370+P378-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 0
LogP 1.074
H_Acceptors 0
H_Donors 0
Rotatable_Bonds 2

Other Classifications

General Reagents Reductive Reagents Silane Reductive Reagents

Material Science Organic-Inorganic Hybrid Materials A silane coupling agent

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Synthesis Organometallic Reagents Organosilicon Hydrosilanes

Chemical Synthesis Synthetic Reagents Reduction Silanes

Key Words

1,4-Bis(dimethylsilyl)benzene sigma1,4-Bis(dimethylsilyl)benzene manufacturer1,4-Bis(dimethylsilyl)benzene price1,4-Bis(dimethylsilyl)benzene structure1,4-Bis(dimethylsilyl)benzene SDSbuy 1,4-Bis(dimethylsilyl)benzene1,4-Bis(dimethylsilyl)benzene supplier1,4-Bis(dimethylsilyl)benzene uses1,4-Bis(dimethylsilyl)benzene molecular weightprice of 1,4-Bis(dimethylsilyl)benzene1,4-Bis(dimethylsilyl)benzene chemical name formula of 1,4-Bis(dimethylsilyl)benzene

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1,4-Bis(dimethylsilyl)benzene

CAS No. 2488-01-9

Recommended Products