1-(3-Fluorophenyl)cyclopropane-1-carboxylic acid

Name: 1-(3-Fluorophenyl)cyclopropane-1-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 248588-33-2
Cat. No. CS-0060402
Purity≥97%
MDL No.MFCD07374443

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(3-Fluorophenyl)cyclopropane-1-carboxylic acid|CS-0060402

Structure of 248588-33-2

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 248588-33-2
Cat. No. CS-0060402
Purity ≥97%
MDL No. MFCD07374443
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₉FO₂
Molecular Weight 180.18
Synonym(s) 1-(3-Fluorophenyl)cyclopropanecarboxylic acid
SMILES C1=CC(=CC(=C1)F)C2(CC2)C(=O)O

Description

1-(3-Fluorophenyl)cyclopropane-1-carboxylic acid features a rigid cyclopropane ring fused to an electron-deficient fluorinated phenyl moiety, delivering enhanced metabolic stability and precise spatial orientation. This structural motif enables efficient integration into bioactive scaffolds for medicinal chemistry campaigns targeting CNS disorders and kinase inhibition.

Application

1-(3-Fluorophenyl)cyclopropane-1-carboxylic acid serves as a valuable building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard functional group manipulations. Its cyclopropyl carboxylic acid motif exhibits enhanced metabolic stability and conformational rigidity, facilitating target engagement in CNS and oncology drug discovery. The molecule demonstrates excellent bench stability and compatibility with common coupling reactions, simplifying purification and scale-up in multi-step syntheses.

Synthesis

Route1
- In-stock
  
  501-00-8
- 107-04-0
- ~%
- In-stock
  
  248588-33-2
References
- WO2004/43911 A2, ; Page 49-50 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 37.3
LogP 1.9419
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Fatty ring compounds Cyclopropane compounds

Key Words

248588-33-2 sigma248588-33-2 manufacturer248588-33-2 price248588-33-2 structure248588-33-2 SDSbuy 248588-33-2248588-33-2 supplier248588-33-2 uses248588-33-2 molecular weightprice of 248588-33-2248588-33-2 chemical name formula of 248588-33-2

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

1-(3-Fluorophenyl)cyclopropane-1-carboxylic acid

CAS No. 248588-33-2

Recommended Products