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Structure of 247564-66-5
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4,6-Difluoroindole-2-carboxylic acid features a strategically fluorinated indole core that enhances metabolic stability and modulates electronic properties. The carboxylic acid moiety enables direct conjugation in peptide coupling reactions, while the difluoro substitution improves lipophilicity and membrane permeability. This compound serves as a key building block for bioactive heterocycles in medicinal chemistry.
4,6-Difluoroindole-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of fluorinated indole scaffolds into bioactive molecules. The difluoro substitution enhances metabolic stability and modulates electronic properties, while the carboxylic acid group facilitates coupling reactions with amines, alcohols, or via activated esters. Its bench-stable nature and compatibility with standard peptide and heterocyclic synthesis protocols make it well-suited for iterative library construction and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: