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CS-W001157 4
Total: USD 88.00

2-(Triphenyl-l5-phosphanylidene)propanal

  • CAS No. 24720-64-7

  • Cat. No. CS-0113100
  • Purity≥97%
  • MDL No.MFCD00075596

*For research and further manufacturing use only, not for direct human use.

2-(Triphenyl-l5-phosphanylidene)propanal|CS-0113100

Structure of 24720-64-7

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General Information

  • CAS No. 24720-64-7
  • Cat. No. CS-0113100
  • Purity ≥97%
  • MDL No. MFCD00075596
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₁₉OP
  • Molecular Weight 318.35
  • Synonym(s) 2-(Triphenylphosphoranylidene)propionaldehyde
  • SMILES CC(C=O)=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

Description

Reactant for:Preparation of acitretin analogs with antitumor activityStereoselective synthesis of essential building blocks of phorboxazole A via hetero Diels-Alder and stereoselective hetero-Michael addition/equilibrationPreparation of C1-C14 fragment of sarcoglaucol-16-one via Z-selective ando-type Horner-Wadsworth-Emmons olefinationWittig reactionsSynthesis of ring-expanded and epothilone-hybridized macrosphelide analogs as apoptosis-inducing agentsPreparation of phosphonic acid-containing analogs of mycophenolic acid as inhibitors of IMPDH

Application

2-(Triphenylphosphanylidene)propanal serves as a versatile phosphorus ylide precursor in Wittig-type reactions, enabling efficient olefination of aldehydes and ketones under mild conditions. Its bench-stable nature and predictable reactivity facilitate the synthesis of α,β-unsaturated carbonyl compounds with high stereoselectivity. Widely used in complex molecule assembly, it functions reliably in standard organic workflows requiring controlled C=C bond formation.

Synthesis

  • Route1
    • In-stock
      Ethyltriphenylphosphonium iodide|CS-W011657
      4736-60-1
    • null|null
      109-94-4
    • ~80%
    • In-stock
      2-(Triphenyl-l5-phosphanylidene)propanal|CS-0113100
      24720-64-7

    References

    • Kiyooka, Syun-Ichi; Hena, Mostofa A. Journal of Organic Chemistry, 1999 , vol. 64, # 15 p. 5511 - 5523
  • Route2
    • null|null
      82248-14-4
    • ~%
    • In-stock
      2-(Triphenyl-l5-phosphanylidene)propanal|CS-0113100
      24720-64-7

    References

    • Chemische Berichte, , vol. 117, # 4 p. 1561 - 1571
  • Route3
    • null|null
      90601-11-9
    • ~%
    • In-stock
      2-(Triphenyl-l5-phosphanylidene)propanal|CS-0113100
      24720-64-7

    References

    • Chemische Berichte, , vol. 117, # 4 p. 1561 - 1571

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.3717
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   4

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