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CS-W001157 4
Total: USD 88.00

Ethyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide

  • CAS No. 24683-21-4

  • Cat. No. CS-0084729
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide|CS-0084729

Structure of 24683-21-4

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General Information

  • CAS No. 24683-21-4
  • Cat. No. CS-0084729
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁NO₅S
  • Molecular Weight 269.27
  • Synonym(s) Ethyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide (Piroxicam Impurity H)
  • SMILES O=S1(C2=CC=CC=C2C(O)=C(C(OCC)=O)N1)=O

Synthesis

  • Route1
    • Ethyl 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3H)-yl)acetate|CS-0127725
      24683-20-3
    • ~68%
    • Ethyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide|CS-0084729
      24683-21-4

    References

    • Koczian, Kristof; Voelgyi, Gergely; Koekoesi, Jozsef; Noszal, Bela Helvetica Chimica Acta, 2007 , vol. 90, # 9 p. 1681 - 1690
  • Route2

    References

    • Koczian, Kristof; Voelgyi, Gergely; Koekoesi, Jozsef; Noszal, Bela Helvetica Chimica Acta, 2007 , vol. 90, # 9 p. 1681 - 1690
  • Route3
    • Methyl 2-(1,1-dioxido-3-oxobenzo[d]isothiazol-2(3h)-yl)acetate|CS-0302107
      6639-62-9
    • null|null
      141-52-6
    • ~75%
    • Methyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide|CS-0084726
      35511-14-9
    • Ethyl 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide|CS-0084729
      24683-21-4

    References

    • Schapira, Celia B.; Perillo, Isabel A.; Lamdan, Samuel Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1281 - 1288

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   92.7
  • LogP   0.7682
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

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