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CS-W001157 4
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6-Methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylic acid

  • CAS No. 24667-07-0

  • Cat. No. CS-0529447
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylic acid|CS-0529447

Structure of 24667-07-0

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General Information

  • CAS No. 24667-07-0
  • Cat. No. CS-0529447
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆F₃NO₃
  • Molecular Weight 221.13
  • Synonym(s) 6-methyl-2-oxo-4-trifluoromethyl-1,2-dihydro-pyridine-3-carboxylic acid
  • SMILES O=C(C1=C(C(F)(F)F)C=C(C)NC1=O)O

Synthesis

  • Route1
    • Methyl 6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylate|CS-0529436
      1421673-57-5
    • ~%
    • 6-Methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylic acid|CS-0529447
      24667-07-0

    References

    • Tilley, Jefferson W.; Sidduri, Achyutharao; Lou, Jianping; Kaplan, Gerry; Tare, Nadine; Cavallo, Gary; Frank, Karl; Pamidimukkala, Anjula; Choi, Duk Soon; Gerber, Louise; Railkar, Aruna; Renzetti, Louis Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 4 p. 1036 - 1040

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   70.16
  • LogP   1.40032
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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