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CS-W001157 4
Total: USD 88.00

Grubbs 2nd

  • CAS No. 246047-72-3

  • Cat. No. CS-0020122
  • Purity≥95%
  • MDL No.MFCD03453237

*For research and further manufacturing use only, not for direct human use.

Grubbs 2nd|CS-0020122

Structure of 246047-72-3

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General Information

  • CAS No. 246047-72-3
  • Cat. No. CS-0020122
  • Purity ≥95%
  • MDL No. MFCD03453237
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₆H₆₅Cl₂N₂PRu
  • Molecular Weight 848.97
  • Synonym(s) Tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene][benzylidine]Ruthenium(IV)dichloride
  • SMILES CC1=CC(C)=CC(C)=C1N2C([Ru](Cl)(Cl)([P](C3CCCCC3)(C4CCCCC4)C5CCCCC5)=CC6=CC=CC=C6)N(C7=C(C)C=C(C)C=C7C)CC2

Description

Grubbs Catalyst M204 can be used as a catalyst for ring-closing metathesis (RCM), cross-metathesis, and ring-opening metathesis polymerization (ROMP). It is also used to synthesize trisubstituted olefins with excellent functional group tolerance and selectivity via cross-metathesis and ring closing metathesis reactions.It can also be used as a catalyst:To synthesize coumarins from phenolic compounds via RCM.To cleave secondary (E)-allyl vic-diols to aldehydes.For small scale and high throughput uses, product is also available as ChemBeads (919764) Learn more about our metathesis catalysts

Application

Grubbs 2nd-generation catalyst enables efficient ring-closing metathesis (RCM) and cross-metathesis reactions under mild conditions, facilitating the construction of medium- to large-ring cyclic olefins. Its robustness, functional group tolerance, and operational simplicity make it a preferred choice for complex molecule synthesis, including natural products and pharmaceutical intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Warning
UN#: 1325
Class : 4.1
Packing Group : Ⅲ
Hazard Statements : H228
Precautionary Statements : P210-P240-P241-P280-P370+P378

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Computational Chemistry Data

  • TPSA   6.48
  • LogP   13.658
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   8

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