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CS-W001157 4
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1-(3-Aminopropyl)azepan-2-one

  • CAS No. 24566-95-8

  • Cat. No. CS-0155358
  • Purity≥95%
  • MDL No.MFCD00036060

*For research and further manufacturing use only, not for direct human use.

1-(3-Aminopropyl)azepan-2-one|CS-0155358

Structure of 24566-95-8

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General Information

  • CAS No. 24566-95-8
  • Cat. No. CS-0155358
  • Purity ≥95%
  • MDL No. MFCD00036060
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈N₂O
  • Molecular Weight 170.25
  • Synonym(s) N-(3-Aminopropyl)-EPSILON-caprolactam
  • SMILES C1CCC(=O)N(CC1)CCCN

Description

1-(3-Aminopropyl)azepan-2-one features a flexible azepan-2-one scaffold bearing a primary amine at the terminal end of a three-carbon chain. This combination delivers enhanced solubility and nucleophilicity, enabling efficient incorporation into macrocyclic architectures and bioconjugation workflows under standard conditions.

Synthesis

  • Route1

    References

    • Cheng; Liu Synthetic Communications, 1993 , vol. 23, # 22 p. 3191 - 3194
  • Route2

    References

    • Heidelberger, Christian; Guggisberg, Armin; Stephanou, Euripides; Hesse, Manfred Helvetica Chimica Acta, 1981 , vol. 64, # 2 p. 399 - 406
  • Route3

    References

    • Cheng; Liu Synthetic Communications, 1993 , vol. 23, # 22 p. 3191 - 3194

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P261-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   46.33
  • LogP   0.7378
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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