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Structure of 245524-94-1
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4-Chloro-6-nitro-1H-indole is a heterocyclic building block featuring a chlorinated and nitro-substituted indole core. This electron-deficient scaffold enables direct functionalization in cross-coupling and cyclization reactions. The para-nitro group enhances reactivity while maintaining stability under standard conditions, making it suitable for advanced synthetic sequences in medicinal chemistry and materials science.
4-Chloro-6-nitro-1H-indole serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted indole scaffolds via palladium-catalyzed cross-coupling and nucleophilic substitution reactions. The ortho-directed reactivity of the nitro group facilitates regioselective functionalization, while the chloro substituent provides compatibility with standard coupling protocols. Its bench-stable nature and predictable reactivity profile make it well-suited for medicinal chemistry applications and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: