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CS-W001157 4
Total: USD 88.00

Methyl 3-(methylamino)propanoate

  • CAS No. 24549-12-0

  • Cat. No. CS-0150994
  • Purity≥98%
  • MDL No.MFCD11505527

*For research and further manufacturing use only, not for direct human use.

Methyl 3-(methylamino)propanoate|CS-0150994

Structure of 24549-12-0

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General Information

  • CAS No. 24549-12-0
  • Cat. No. CS-0150994
  • Purity ≥98%
  • MDL No. MFCD11505527
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₁NO₂
  • Molecular Weight 117.15
  • Synonym(s) None
  • SMILES O=C(OC)CCNC

Description

Methyl 3-(methylamino)propanoate features a primary ester group flanked by a methylamino substituent, delivering enhanced solubility and reactivity in polar media. This amine-functionalized ester integrates readily into peptide-like scaffolds and serves as a key intermediate in bioactive molecule synthesis.

Application

Methyl 3-(methylamino)propanoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to bioactive amine-containing scaffolds. Its ester functionality facilitates downstream transformations such as hydrolysis, amidation, and reductive amination, while the pendant primary amine supports derivatization and salt formation. The molecule exhibits good bench stability and ease of purification, making it suitable for use in medicinal chemistry campaigns and process development workflows.

Synthesis

  • Route1
    • null|null
      292638-85-8
    • null|null
      74-89-5
    • ~97%
    • In-stock
      Methyl 3-(methylamino)propanoate|CS-0150994
      24549-12-0

    References

    • Dujols, Frederic; Jollet, Philippe; Mulliez, Michel Phosphorus, Sulfur and Silicon and Related Elements, 1998 , vol. 134-135, p. 231 - 254
  • Route2
    • Methyl 3-(benzyl(methyl)amino)propanoate|CS-0300431
      17946-01-9
    • ~77%
    • In-stock
      Methyl 3-(methylamino)propanoate|CS-0150994
      24549-12-0

    References

    • Rosenberg, Saul H.; Rapoport, Henry Journal of Organic Chemistry, 1985 , vol. 50, # 21 p. 3979 - 3982
  • Route3
    • null|null
      64-17-5
    • Methyl 3-(benzyl(methyl)amino)propanoate|CS-0300431
      17946-01-9
    • ~%
    • In-stock
      Methyl 3-(methylamino)propanoate|CS-0150994
      24549-12-0
    • In-stock
      Ethyl 3-(methylamino)propanoate|CS-M0246
      2213-08-3

    References

    • KING'S COLLEGE LONDON; BLOWER, Philip, John; TORRES MARTIN DE ROSALES, Rafael Patent: WO2010/116132 A2, 2010 ; Location in patent: Page/Page column 42; 43 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   -0.2311
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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