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Structure of 2450-26-2
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4-Hydroxy-3-methoxy-2-nitrobenzaldehyde features a nitro group at the ortho position relative to the aldehyde, enhancing electrophilicity for nucleophilic addition. The phenolic hydroxyl and methoxy substituents provide steric and electronic modulation, enabling selective functionalization in complex synthesis. This bench-stable reagent integrates readily into multi-step sequences requiring controlled reactivity.
4-Hydroxy-3-methoxy-2-nitrobenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinones, and bioactive heterocycles. Its ortho-nitro and aldehyde functionalities facilitate sequential transformations under mild conditions, while the phenolic hydroxyl and methoxy groups offer sites for derivatization. The compound exhibits good bench stability and is amenable to standard purification techniques, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: