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Structure of 243863-36-7
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This difluoromethoxy-substituted aniline derivative features a para-difluoromethoxy group that enhances metabolic stability and lipophilicity, enabling efficient integration into bioactive scaffolds. The primary amine facilitates conjugation and derivatization under standard coupling conditions.
(2-(Difluoromethoxy)phenyl)methanamine serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its difluoromethoxy group imparts enhanced metabolic stability and modulated lipophilicity, while the primary amine facilitates straightforward derivatization via acylation, alkylation, or coupling reactions. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for scalable synthesis and structure-activity studies.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501
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Lot numbers can be found on the outside label of a product: