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Structure of 243835-70-3
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6-Chloropyridine-3,4-dicarboxylic acid features a pyridine core functionalized with chlorine and two carboxylic acid groups at the 6-, 3-, and 4-positions. This arrangement imparts strong electron-withdrawing character and enhances solubility in polar solvents. The molecule serves as a valuable scaffold for constructing bioactive heterocycles and metal-organic frameworks. Its stability under standard conditions supports reliable use in synthetic workflows.
6-Chloropyridine-3,4-dicarboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the 2-position via palladium-catalyzed cross-coupling. Its carboxylic acid groups facilitate salt formation and derivatization, while the chlorine atom provides a reliable handle for nucleophilic substitution. The molecule exhibits excellent bench stability and compatibility with standard purification techniques, making it well-suited for use in medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: