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tert-Butyl 7-methyl-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate

  • CAS No. 243641-37-4

  • Cat. No. CS-0081051
  • Purity≥98%
  • MDL No.MFCD06659018

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 7-methyl-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxylate|CS-0081051

Structure of 243641-37-4

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General Information

  • CAS No. 243641-37-4
  • Cat. No. CS-0081051
  • Purity ≥98%
  • MDL No. MFCD06659018
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₀N₂O₂
  • Molecular Weight 248.32
  • Synonym(s) 7-METHYL-3,4-DIHYDRO-2H-[1,8]NAPHTHYRIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • SMILES CC1=CC=C(CCCN2C(OC(C)(C)C)=O)C2=N1

Synthesis

  • Route1

    References

    • AC IMMUNE S.A.; KROTH, Heiko; FROESTL, Wolfgang; PFEIFER, Andrea; MUHS, Andreas Patent: WO2011/45383 A2, 2011 ; Location in patent: Page/Page column 92 ;
  • Route2

    References

    • SmithKline Beecham Corporation Patent: US6495560 B1, 2002 ;
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 10 p. 2679 - 2684

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

  • TPSA   42.43
  • LogP   3.07772
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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