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CS-W001157 4
Total: USD 88.00

4-Bromoisothiazole

  • CAS No. 24340-77-0

  • Cat. No. CS-0012647
  • Purity≥98%
  • MDL No.MFCD06657593

*For research and further manufacturing use only, not for direct human use.

4-Bromoisothiazole|CS-0012647

Structure of 24340-77-0

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General Information

  • CAS No. 24340-77-0
  • Cat. No. CS-0012647
  • Purity ≥98%
  • MDL No. MFCD06657593
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₂BrNS
  • Molecular Weight 164.02
  • Synonym(s) 4-Bromoisothiazole USP/EP/BP
  • SMILES BrC1=CSN=C1

Description

4-Bromoisothiazole serves as a valuable heterocyclic scaffold in synthetic organic chemistry, offering a reactive bromine handle for cross-coupling transformations. The molecule features a stable isothiazole core with electron-withdrawing bromine substitution at the 4-position, enabling selective functionalization in medicinal chemistry and materials development.

Application

4-Bromoisothiazole serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the 4-position via palladium-catalyzed cross-coupling reactions. Its stable heterocyclic core exhibits good bench longevity and compatibility with diverse reaction conditions, facilitating access to substituted isothiazoles for medicinal chemistry and materials science applications.

Synthesis

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    • In-stock
      4-Bromoisothiazole|CS-0012647
      24340-77-0

    References

    • Journal of Medicinal Chemistry, , vol. 11, # 1 p. 70 - 73

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   1.9056
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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