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CS-W001157 4
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2-Bromo-1-phenylethan-1-ol

  • CAS No. 2425-28-7

  • Cat. No. CS-W021594
  • Purity≥95%
  • MDL No.MFCD00540454

*For research and further manufacturing use only, not for direct human use.

2-Bromo-1-phenylethan-1-ol|CS-W021594

Structure of 2425-28-7

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General Information

  • CAS No. 2425-28-7
  • Cat. No. CS-W021594
  • Purity ≥95%
  • MDL No. MFCD00540454
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BrO
  • Molecular Weight 201.06
  • Synonym(s) 2-Bromo-1-phenylethanol
  • SMILES OC(C1=CC=CC=C1)CBr

Description

2-Bromo-1-phenylethan-1-ol features a chiral benzylic center bearing both bromine and hydroxyl groups, enabling direct functionalization in asymmetric synthesis. This bench-stable reagent integrates readily into C–C bond-forming sequences and serves as a precursor for enantioselective transformations.

Application

2-Bromo-1-phenylethan-1-ol serves as a versatile building block in synthetic organic chemistry, enabling efficient access to phenethyl derivatives via substitution and elimination reactions. Its bromide functionality facilitates nucleophilic displacement under mild conditions, while the benzylic alcohol offers compatibility with oxidation, protection, and coupling protocols. The compound exhibits good bench stability and is readily purified by distillation or chromatography, supporting its use in iterative synthesis and scale-up applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.1149
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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