2-Amino-1-morpholinoethanone hydrochloride

Name: 2-Amino-1-morpholinoethanone hydrochloride
Brand: ChemScene
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CAS No. 24152-96-3
Cat. No. CS-0199378
Purity≥98%
MDL No.MFCD07366740

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2-Amino-1-morpholinoethanone hydrochloride|CS-0199378

Structure of 24152-96-3

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General Information

CAS No. 24152-96-3
Cat. No. CS-0199378
Purity ≥98%
MDL No. MFCD07366740
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₃ClN₂O₂
Molecular Weight 180.63
Synonym(s) 2-Amino-1-(4-morpholinyl)-ethanone HCl
SMILES O=C(CN)N1CCOCC1.Cl

Description

2-Amino-1-morpholinoethanone hydrochloride features a morpholino-bearing amide scaffold with enhanced solubility and stability under standard conditions. This bench-stable derivative integrates readily into peptide conjugation workflows, serving as a versatile intermediate for bioconjugate synthesis and medicinal chemistry applications.

Application

2-Amino-1-morpholinoethanone hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to morpholine-containing scaffolds. Its amine and ketone functionalities support diverse transformations, including amidation and reductive amination, while the hydrochloride salt enhances solubility and bench stability for routine synthetic workflows.

Synthesis

Route1
- 114703-81-0
- ~92%
- In-stock
  
  24152-96-3
References
- Venuti, Michael C.; Alvarez, Robert; Bruno, John J.; Strosberg, Arthur M.; Gu, Leo; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 11 p. 2145 - 2152

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 55.56
LogP -0.7743
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Key Words

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2-Amino-1-morpholinoethanone hydrochloride

CAS No. 24152-96-3

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