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Structure of 241479-74-3
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This chiral nitrile features a (2S,3R)-configured core with a 1H-1,2,4-triazolyl group and a 2,5-difluorophenyl substituent. The hydroxy and methyl groups at C3 and C2 provide stereochemical control, while the triazolyl moiety enhances solubility and hydrogen-bonding capacity. Bench-stable under standard conditions, it serves as a key intermediate in the synthesis of bioactive heterocycles.
(2S,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile serves as a chiral building block for medicinal chemistry campaigns, enabling efficient access to triazole-containing scaffolds via standard coupling and functional group interconversions. Its bench-stable hydroxyl and nitrile groups tolerate diverse reaction conditions, while the 2,5-difluorophenyl moiety enhances metabolic stability and modulates lipophilicity in target molecule design.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: