6-Bromo-N,N-bis(4-methoxybenzyl)-4-methyl-5-(trifluoromethyl)pyridin-2-amine

Name: 6-Bromo-N,N-bis(4-methoxybenzyl)-4-methyl-5-(trifluoromethyl)pyridin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2411793-14-9
Cat. No. CS-0492110
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Bromo-N,N-bis(4-methoxybenzyl)-4-methyl-5-(trifluoromethyl)pyridin-2-amine|CS-0492110

Structure of 2411793-14-9

Size

Price

Quantity

* Please select Quantity before adding items.

Description

6-Bromo-N,N-bis(4-methoxybenzyl)-4-methyl-5-(trifluoromethyl)pyridin-2-amine features a sterically hindered pyridine core with electron-withdrawing trifluoromethyl and bromo substituents, enabling precise coupling in late-stage functionalization. The bis(4-methoxybenzyl) amine moiety enhances solubility and stability under standard conditions, while the methyl group provides a strategic handle for further derivatization in medicinal chemistry campaigns.

Application

6-Bromo-N,N-bis(4-methoxybenzyl)-4-methyl-5-(trifluoromethyl)pyridin-2-amine serves as a versatile building block for late-stage functionalization in medicinal chemistry. The bromine at the 6-position enables palladium-catalyzed cross-coupling reactions, while the trifluoromethyl group enhances metabolic stability and lipophilicity. The bis(4-methoxybenzyl) protection offers robust orthogonality and ease of purification, with the methyl substituent providing steric control during subsequent transformations.

General Information

CAS No. 2411793-14-9
Cat. No. CS-0492110
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₂₂BrF₃N₂O₂
Molecular Weight 495.33
Synonym(s) None
SMILES COC1=CC=C(C=C1)CN(CC2=CC=C(OC)C=C2)C3=NC(Br)=C(C(F)(F)F)C(C)=C3

Computational Chemistry Data

TPSA 34.59
LogP 6.39532
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2411793-14-9 sigma2411793-14-9 manufacturer2411793-14-9 price2411793-14-9 structure2411793-14-9 SDSbuy 2411793-14-92411793-14-9 supplier2411793-14-9 uses2411793-14-9 molecular weightprice of 2411793-14-92411793-14-9 chemical name formula of 2411793-14-9

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Bromo-N,N-bis(4-methoxybenzyl)-4-methyl-5-(trifluoromethyl)pyridin-2-amine

CAS No. 2411793-14-9

Recommended Products