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CS-W001157 4
Total: USD 88.00

2,4,6-Tribromopyridine

  • CAS No. 2408-70-0

  • Cat. No. CS-W006226
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,4,6-Tribromopyridine|CS-W006226

Structure of 2408-70-0

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General Information

  • CAS No. 2408-70-0
  • Cat. No. CS-W006226
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂Br₃N
  • Molecular Weight 315.79
  • Synonym(s) 2,3-DIHYDROBENZIMIDAZOL-2-ONE,CRM STANDARD
  • SMILES BrC1=CC(Br)=CC(Br)=N1

Description

5,5',6,6'-Tetrahydroxy-3,3,3',3'- tetramethyl-1,1'-spirobisindane is used in the preparation of 4,7,4',7'-tetrabromo-3,3,3',3'-tetramethyl-2,3,2',3'-tetrahydro-[1,1']spirobiindene-5,6,5',6'-tetraol by bromination using bromine.

Application

2,4,6-Tribromopyridine serves as a versatile building block in synthetic organic chemistry, enabling regioselective functionalization at the pyridine ring due to its electronically deactivated yet sterically accessible bromine substituents. It functions as a key intermediate in the construction of substituted heterocycles and facilitates palladium-catalyzed cross-coupling reactions under standard conditions. The compound exhibits good bench stability and is readily handled, making it suitable for use in iterative synthesis workflows and API-related scaffold development.

Synthesis

  • Route1
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      98027-81-7
    • null|null
      506-96-7
    • ~63%
    • In-stock
      2,4,6-Tribromopyridine|CS-W006226
      2408-70-0

    References

    • Huang, Hai-Fang; Xu, Shi-Hua; He, Yan-Bo; Zhu, Cai-Cai; Fan, He-Liang; Zhou, Xue-Hua; Gao, Xi-Cun; Dai, Yan-Feng Dyes and Pigments, 2013 , vol. 96, # 3 p. 705 - 713
  • Route2

    References

    • Chemische Berichte, , vol. 122, p. 589 - 592
  • Route3
    • null|null
      25373-69-7
    • ~%
    • In-stock
      2,4,6-Tribromopyridine|CS-W006226
      2408-70-0

    References

    • Chemische Berichte, , vol. 122, p. 589 - 592

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   3.3691
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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