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CS-W001157 4
Total: USD 88.00

4-Hydroxycyclohexanecarbonitrile

  • CAS No. 24056-34-6

  • Cat. No. CS-D1577
  • Purity≥96%
  • MDL No.MFCD13688990

*For research and further manufacturing use only, not for direct human use.

4-Hydroxycyclohexanecarbonitrile|CS-D1577

Structure of 24056-34-6

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General Information

  • CAS No. 24056-34-6
  • Cat. No. CS-D1577
  • Purity ≥96%
  • MDL No. MFCD13688990
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁NO
  • Molecular Weight 125.17
  • Synonym(s) 4-hydroxycyclohexane-1-carbonitrile
  • SMILES N#CC1CCC(O)CC1

Description

4-Hydroxycyclohexanecarbonitrile features a hydroxyl group and nitrile functionality on a cyclohexane ring, enabling dual reactivity for synthetic transformations. This bench-stable compound integrates readily into complex molecular architectures, serving as a key intermediate in medicinal chemistry and polymer science.

Application

4-Hydroxycyclohexanecarbonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of cyclic scaffolds via nucleophilic substitution or cyclization reactions. The pendant hydroxyl and nitrile groups offer orthogonal reactivity for derivatization, while the cyclohexane core provides conformational stability. Its bench-stable nature and compatibility with standard purification methods make it well-suited for multi-step synthesis workflows.

Synthesis

  • Route1

    References

    • Annales de Chimie (Cachan, France), , vol. <12> 10, p. 497,531 Bulletin de la Societe Chimique de France, , p. 610,612
  • Route2
    • In-stock
      4-Hydroxycyclohexanone|CS-D0911
      13482-22-9
    • null|null
      38622-91-2
    • ~%
    • In-stock
      4-Hydroxycyclohexanecarbonitrile|CS-D1577
      24056-34-6

    References

    • Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 35, # 11 p. 1451 - 1454

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   44.02
  • LogP   1.06108
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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