Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylate

  • CAS No. 23951-66-8

  • Cat. No. CS-0169593
  • Molecule weight204.18
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylate|CS-0169593

Structure of 23951-66-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 23951-66-8
  • Cat. No. CS-0169593
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈N₂O₃
  • Molecular Weight 204.18
  • Synonym(s) methyl 4-oxopyrido[1,2-a]pyrimidine-2-carboxylate
  • SMILES O=C1C=C(C(OC)=O)N=C2C=CC=CN21

Description

Methyl 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylate features a fused pyridopyrimidine core with a ketone at C4 and an ester group at C2, enabling integration into heterocyclic scaffolds. This electron-deficient system facilitates transition metal-catalyzed couplings and serves as a key intermediate in the synthesis of bioactive nitrogen-rich compounds.

Application

Methyl 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylate serves as a versatile building block for constructing pyrido[1,2-a]pyrimidine scaffolds prevalent in medicinal chemistry. Its electrophilic C4 carbonyl and ester functionalities enable selective functionalization via nucleophilic addition, condensation, or transition-metal-catalyzed coupling reactions. The compound exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis of heterocyclic intermediates and API candidates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   60.67
  • LogP   0.4811
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 23951-66-8 sigma23951-66-8 manufacturer23951-66-8 price23951-66-8 structure23951-66-8 SDSbuy 23951-66-823951-66-8 supplier23951-66-8 uses23951-66-8 molecular weightprice of 23951-66-823951-66-8 chemical name formula of 23951-66-8
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label