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Structure of 23951-66-8
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Methyl 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylate features a fused pyridopyrimidine core with a ketone at C4 and an ester group at C2, enabling integration into heterocyclic scaffolds. This electron-deficient system facilitates transition metal-catalyzed couplings and serves as a key intermediate in the synthesis of bioactive nitrogen-rich compounds.
Methyl 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylate serves as a versatile building block for constructing pyrido[1,2-a]pyrimidine scaffolds prevalent in medicinal chemistry. Its electrophilic C4 carbonyl and ester functionalities enable selective functionalization via nucleophilic addition, condensation, or transition-metal-catalyzed coupling reactions. The compound exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis of heterocyclic intermediates and API candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: