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CS-W001157 4
Total: USD 88.00

3-(4-Aminophenyl)propionic acid

  • CAS No. 2393-17-1

  • Cat. No. CS-W019508
  • Purity≥98%
  • MDL No.MFCD00017118

*For research and further manufacturing use only, not for direct human use.

3-(4-Aminophenyl)propionic acid|CS-W019508

Structure of 2393-17-1

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General Information

  • CAS No. 2393-17-1
  • Cat. No. CS-W019508
  • Purity ≥98%
  • MDL No. MFCD00017118
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₂
  • Molecular Weight 165.19
  • Synonym(s) None
  • SMILES O=C(O)CCC1=CC=C(N)C=C1

Description

3-(4-Aminophenyl)propionic acid features a para-aminophenyl group linked via a propionic acid chain, enabling integration into bioconjugation workflows. The electron-rich aromatic ring and amine functionality facilitate coupling reactions, while the carboxylic acid serves as a robust anchor for peptide synthesis or surface functionalization under standard conditions.

Application

3-(4-Aminophenyl)propionic acid serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient access to biologically relevant aryl-aliphatic scaffolds. Its amine and carboxylic acid functionalities support diverse transformations including amidation, esterification, and coupling reactions, while demonstrating good bench stability and ease of purification. Functions effectively in standard peptide coupling and heterocycle formation protocols.

Synthesis

  • Route1

    References

    • WO2006/20070 A2, ; Page/Page column 50 ;
  • Route2
    • (E)-3-(4-Nitrophenyl)acrylic acid|CS-0076962
      882-06-4
    • ~88%
    • In-stock
      3-(4-Aminophenyl)propionic acid|CS-W019508
      2393-17-1

    References

    • Journal of Medicinal Chemistry, , vol. 44, # 25 p. 4453 - 4461
  • Route3
    • (E)-3-(4-Aminophenyl)acrylic acid|CS-0885995
      17570-30-8
    • ~96%
    • In-stock
      3-(4-Aminophenyl)propionic acid|CS-W019508
      2393-17-1

    References

    • Journal of Medicinal Chemistry, , vol. 37, # 12 p. 1841 - 1849

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.286
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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