2-Amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile

Name: 2-Amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 23917-22-8
Cat. No. CS-0076892
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile|CS-0076892

Structure of 23917-22-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 23917-22-8
Cat. No. CS-0076892
Purity ≥98%
MDL No. None
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₂N₂S
Molecular Weight 192.28
Synonym(s) 2-Amino-5,6,7,8-tetrahydro-4H-cyclohepta-[b]thiophene-3-carbonitrile
SMILES N#CC1=C(N)SC2=C1CCCCC2

Description

This tetrahydrocycloheptathiochrome derivative features a nitrogen-substituted heterocyclic core with a nitrile group at the 3-position, enabling integration into diverse synthetic scaffolds. The electron-rich ring system supports robust reactivity in transition metal-catalyzed transformations and offers enhanced solubility in polar organic media.

Application

2-Amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused thiophene core with pendant amino and nitrile groups enables diverse functionalization via nucleophilic substitution, coupling reactions, and cyclization protocols. The compound exhibits good bench stability and facilitates the construction of complex scaffolds relevant to kinase inhibitors and bioactive small molecules.

Synthesis

Route1
- 109-77-3
- 502-42-1
- ~99%
- In-stock
  
  23917-22-8
References
- SYNGENTA PARTICIPATIONS AG; SYNGENTA LIMITED Patent: WO2005/44008 A2, 2005 ; Location in patent: Page/Page column 93 ;
Route2
- 10394-94-2
- ~99%
- In-stock
  
  23917-22-8
References
- Feroci, Marta; Chiarotto, Isabella; Rossi, Leucio; Inesi, Achille Advanced Synthesis and Catalysis, 2008 , vol. 350, # 17 p. 2740 - 2746

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 49.81
LogP 2.47088
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic heterocycle compounds Thiophene compounds

Key Words

23917-22-8 sigma23917-22-8 manufacturer23917-22-8 price23917-22-8 structure23917-22-8 SDSbuy 23917-22-823917-22-8 supplier23917-22-8 uses23917-22-8 molecular weightprice of 23917-22-823917-22-8 chemical name formula of 23917-22-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile

CAS No. 23917-22-8

Recommended Products