Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tert-Butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate

  • CAS No. 239074-29-4

  • Cat. No. CS-0047936
  • Purity≥96%
  • MDL No.MFCD03844605

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate|CS-0047936

Structure of 239074-29-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 239074-29-4
  • Cat. No. CS-0047936
  • Purity ≥96%
  • MDL No. MFCD03844605
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₃NO₃
  • Molecular Weight 229.32
  • Synonym(s) None
  • SMILES N(C(OC(C)(C)C)=O)[C@@H]1CC[C@@H](CO)CC1

Description

This bench-stable carbamate derivative features a trans-configured cyclohexyl scaffold bearing a hydroxymethyl group and a tert-butyl carbamate handle. The pendant hydroxymethyl moiety enables selective derivatization, while the robust protecting group facilitates purification and handling in synthetic workflows involving cyclic amines or functionalized cyclohexane intermediates.

Application

tert-Butyl (trans-4-(hydroxymethyl)cyclohexyl)carbamate serves as a stable, bench-ready building block for the synthesis of cyclohexane-based scaffolds. The trans-configured cyclohexyl core provides defined stereochemistry, while the hydroxymethyl group enables downstream functionalization via oxidation, protection, or coupling reactions. The Boc carbamate offers orthogonal protection and facile deprotection under mild acidic conditions, supporting iterative synthetic strategies in medicinal chemistry and natural product synthesis.

Synthesis

  • Route1

    References

    • Almirall, S.A. Patent: EP2527344 A1, 2012 ; Location in patent: Page/Page column 27-28 ; EP 2527344 A1
  • Route2

    References

    • EP2017261 A1, ; Page/Page column 30-31 ;
  • Route3

    References

    • EP1961744 A1, ; Page/Page column 100 ; EP 1961744 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   58.56
  • LogP   2.0622
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 239074-29-4 sigma239074-29-4 manufacturer239074-29-4 price239074-29-4 structure239074-29-4 SDSbuy 239074-29-4239074-29-4 supplier239074-29-4 uses239074-29-4 molecular weightprice of 239074-29-4239074-29-4 chemical name formula of 239074-29-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label