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CS-W001157 4
Total: USD 88.00

6-Hydroxyindole

  • CAS No. 2380-86-1

  • Cat. No. CS-W002438
  • Purity≥98%
  • MDL No.MFCD00152101

*For research and further manufacturing use only, not for direct human use.

6-Hydroxyindole|CS-W002438

Structure of 2380-86-1

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General Information

  • CAS No. 2380-86-1
  • Cat. No. CS-W002438
  • Purity ≥98%
  • MDL No. MFCD00152101
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO
  • Molecular Weight 133.15
  • Synonym(s) None
  • SMILES OC1=CC2=C(C=C1)C=CN2

Description

Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulatorsReactant for asymmetrical synthesis of notoamide J as a potential biosynthetic precursor of prenylated indole alkaloidsReactant for preparation of (quinolinyloxymethyl)isoxazolecarboxylate esters antituberculosis agentsReactant for preparation of indolyl(propanolamine) derivatives as HIV inhibitorsReactant for preparation of indoleoxyacetic acid derivatives as peroxisome proliferator-activated receptor agonistsReactant for preparation of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors

Synthesis

  • Route1
    • null|null
      153805-86-8
    • ~1%
    • In-stock
      6-Hydroxyindole|CS-W002438
      2380-86-1
    • In-stock
      6-Benzyloxyindole|CS-W007642
      15903-94-3

    References

    • EP1541582 A1, ; Page/Page column 39-40 ;
  • Route2

    References

    • Sheppard, George S.; Pireh, Daisy; Carrera, George M.; Bures, Mark G.; Heyman, H. Robin; et al. Journal of Medicinal Chemistry, 1994 , vol. 37, # 13 p. 2011 - 2032
  • Route3

    References

    • Liou, Jing-Ping; Chang, Yi-Ling; Kuo, Fu-Ming; Chang, Chun-Wei; Tseng, Huan-Yi; Wang, Chiung-Chiu; Yang, Yung-Ning; Chang, Jang-Yang; Lee, Shiow-Ju; Hsieh, Hsing-Pang Journal of Medicinal Chemistry, 2004 , vol. 47, # 17 p. 4247 - 4257

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H317-H318-H411
Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   36.02
  • LogP   1.8735
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   0

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