Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 3-bromopropynoate

  • CAS No. 23680-40-2

  • Cat. No. CS-0043861
  • Purity≥95%
  • MDL No.MFCD22989330

*For research and further manufacturing use only, not for direct human use.

Methyl 3-bromopropynoate|CS-0043861

Structure of 23680-40-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 23680-40-2
  • Cat. No. CS-0043861
  • Purity ≥95%
  • MDL No. MFCD22989330
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃BrO₂
  • Molecular Weight 162.97
  • Synonym(s) Methyl 3-bromopropiolate
  • SMILES O=C(OC)C#CBr

Description

Methyl 3-bromopropynoate is a reactive acetylenic ester featuring a bromine-substituted alkyne moiety. This compound integrates readily into cross-coupling and cycloaddition reactions, offering high functional group tolerance. The pendant ester group enables downstream derivatization, while the terminal alkyne facilitates efficient coupling under mild conditions.

Application

Methyl 3-bromopropynoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted alkynes and functionalized heterocycles. Its bromine-substituted alkyne moiety facilitates palladium-catalyzed coupling reactions, including Sonogashira and Stille couplings, with high functional group tolerance. The ester group provides compatibility with standard transformations, while the molecule exhibits good bench stability and ease of purification—key attributes for reliable use in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      922-67-8
    • ~90%
    • In-stock
      Methyl 3-bromopropynoate|CS-0043861
      23680-40-2

    References

    • Leroy Synthetic Communications, 1992 , vol. 22, # 4 p. 567 - 572
  • Route2
    • In-stock
      1-Bromo-2,5-pyrrolidinedione|CS-W008781
      128-08-5
    • null|null
      922-67-8
    • ~85%
    • In-stock
      Methyl 3-bromopropynoate|CS-0043861
      23680-40-2

    References

    • PHARMACIA and UPJOHN COMPANY Patent: WO2004/39815 A2, 2004 ; Location in patent: Page 44 ; WO 2004/039815 A2
  • Route3
    • null|null
      67-56-1
    • 3-Bromopropiolic acid|CS-0372642
      16900-53-1
    • ~73%
    • In-stock
      Methyl 3-bromopropynoate|CS-0043861
      23680-40-2

    References

    • Commercon, A.; Normant, J. F.; Villieras, J. Tetrahedron, 1980 , vol. 36, # 82 p. 1215 - 1222

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05,GHS07
Signal Word : Danger
UN#: 2924
Class : 3,8
Packing Group : Ⅲ
Hazard Statements : H225-H302-H315-H318
Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P270-P280-P302+P352-P330-P362+P364-P370+P378-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.3
  • LogP   0.5152
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Methyl 3-bromopropynoate sigmaMethyl 3-bromopropynoate manufacturerMethyl 3-bromopropynoate priceMethyl 3-bromopropynoate structureMethyl 3-bromopropynoate SDSbuy Methyl 3-bromopropynoateMethyl 3-bromopropynoate supplierMethyl 3-bromopropynoate usesMethyl 3-bromopropynoate molecular weightprice of Methyl 3-bromopropynoateMethyl 3-bromopropynoate chemical name formula of Methyl 3-bromopropynoate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label