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CS-W001157 4
Total: USD 88.00

3-Boc-3,9-Diazaspiro[5.5]undecane hydrochloride

  • CAS No. 236406-47-6

  • Cat. No. CS-W020524
  • Purity≥97%
  • MDL No.MFCD11656757

*For research and further manufacturing use only, not for direct human use.

3-Boc-3,9-Diazaspiro[5.5]undecane hydrochloride|CS-W020524

Structure of 236406-47-6

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General Information

  • CAS No. 236406-47-6
  • Cat. No. CS-W020524
  • Purity ≥97%
  • MDL No. MFCD11656757
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₇ClN₂O₂
  • Molecular Weight 290.83
  • Synonym(s) None
  • SMILES O=C(N1CCC2(CC1)CCNCC2)OC(C)(C)C.Cl

Description

tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate hydrochloride features a rigid spirocyclic scaffold with two nitrogen atoms positioned for strategic functionalization. This bench-stable, moisture-tolerant salt delivers a protected diamine core ideal for medicinal chemistry applications, enabling efficient incorporation into complex heterocycles and bioactive molecule scaffolds.

Application

tert-Butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate hydrochloride serves as a versatile spirocyclic diamine building block, enabling efficient access to complex nitrogen-containing scaffolds. The protected amine functionality offers enhanced solubility and stability, facilitating downstream functionalization in medicinal chemistry campaigns. Its rigid spirocyclic core provides conformational control, while the tert-butyl ester allows for straightforward deprotection under mild acidic conditions, making it well-suited for iterative synthesis and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   2.8089
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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