2-Chloro-N-cyclohexylacetamide

Name: 2-Chloro-N-cyclohexylacetamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 23605-23-4
Cat. No. CS-0076904
Purity≥97%
MDL No.MFCD00085678

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-N-cyclohexylacetamide|CS-0076904

Structure of 23605-23-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 23605-23-4
Cat. No. CS-0076904
Purity ≥97%
MDL No. MFCD00085678
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₄ClNO
Molecular Weight 175.66
Synonym(s) L6TJ AMV1G [WLN]
SMILES O=C(CCl)NC1([H])CCCCC1

Description

2-Chloro-N-cyclohexylacetamide features a cyclohexyl-amide scaffold with a strategically positioned chloro substituent, delivering enhanced lipophilicity and metabolic stability. This configuration supports efficient integration into bioactive scaffolds and enables selective interactions in medicinal chemistry campaigns.

Application

2-Chloro-N-cyclohexylacetamide serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds and peptide-like motifs. Its chloroacetyl moiety facilitates nucleophilic substitution reactions with amines, thiols, and alcohols under mild conditions, offering high functional group tolerance and reliable yields. The cyclohexyl amide group enhances lipophilicity and metabolic stability, making it valuable for optimizing pharmacokinetic profiles. Bench-stable and readily purified by crystallization or column chromatography, it supports scalable synthesis in both academic and industrial R&D workflows.

Synthesis

Route1
- 108-91-8
- 79-04-9
- ~99%
- In-stock
  
  23605-23-4
References
- Cho, Su-Dong; Song, Sang-Yong; Park, Yong-Dae; Kim, Jeum-Jong; Joo, Woo-Hong; Shiro, Motoo; Falck; Shin, Dong-Soo; Yoon, Yong-Jin Tetrahedron Letters, 2003 , vol. 44, # 50 p. 8995 - 8998
Route2
- 108-91-8
- 75-36-5
- ~94%
- In-stock
  
  23605-23-4
References
- NENSIUS RESEARCH A/S; KELLY, Nicholas; WELLEJUS, Anja; JOERGENSEN, Signe, Humle; WEIDNER, Morten, Sloth Patent: WO2011/945 A2, 2011 ; Location in patent: Page/Page column 36 ;
Route3
- In-stock
  
  593-71-5
- 3173-53-3
- ~94%
- In-stock
  
  23605-23-4
References
- Pace, Vittorio; Castoldi, Laura; Holzer, Wolfgang Chemical Communications, 2013 , vol. 49, # 75 p. 8383 - 8385

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS06
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H301-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 29.1
LogP 1.6741
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Fatty ring compounds Cyclohexane compounds

Key Words

2-Chloro-N-cyclohexylacetamide sigma2-Chloro-N-cyclohexylacetamide manufacturer2-Chloro-N-cyclohexylacetamide price2-Chloro-N-cyclohexylacetamide structure2-Chloro-N-cyclohexylacetamide SDSbuy 2-Chloro-N-cyclohexylacetamide2-Chloro-N-cyclohexylacetamide supplier2-Chloro-N-cyclohexylacetamide uses2-Chloro-N-cyclohexylacetamide molecular weightprice of 2-Chloro-N-cyclohexylacetamide2-Chloro-N-cyclohexylacetamide chemical name formula of 2-Chloro-N-cyclohexylacetamide

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-N-cyclohexylacetamide

CAS No. 23605-23-4

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words