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CS-W001157 4
Total: USD 88.00

3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid

  • CAS No. 23598-72-3

  • Cat. No. CS-0085276
  • Molecule weight237.64
  • Purity≥98%
  • MDL No.MFCD00020813

*For research and further manufacturing use only, not for direct human use.

3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid|CS-0085276

Structure of 23598-72-3

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General Information

  • CAS No. 23598-72-3
  • Cat. No. CS-0085276
  • Purity ≥98%
  • MDL No. MFCD00020813
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₈ClNO₃
  • Molecular Weight 237.64
  • Synonym(s) None
  • SMILES O=C(C1=C(C)ON=C1C2=C(Cl)C=CC=C2)O

Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standardsThese Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Synthesis

  • Route1

    References

    • WO2012/164355 A1, ; Page/Page column 9-10 ;
  • Route2
    • Ethyl 3-(2-chlorophenyl)-5-methylisoxazole-4-carboxylate|CS-0672732
      83817-50-9
    • ~99%
    • 3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid|CS-0085276
      23598-72-3

    References

    • Xin, Zhili; Zhao, Hongyu; Serby, Michael D.; Liu, Bo; Schaefer, Verlyn G.; Falls, Douglas H.; Kaszubska, Wiweka; Colins, Christine A.; Sham, Hing L.; Liu, Gang Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1201 - 1204
  • Route3
    • 2-Chloro-n-hydroxybenzene-1-carbonimidoyl chloride|CS-0237345
      29568-74-9
    • ~%
    • 3-(2-Chlorophenyl)-5-methylisoxazole-4-carboxylic acid|CS-0085276
      23598-72-3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 4 p. 1201 - 1204

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.33
  • LogP   3.00162
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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