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CS-W001157 4
Total: USD 88.00

Ethyl 3-(benzylamino)propanoate

  • CAS No. 23583-21-3

  • Cat. No. CS-W015263
  • Purity≥97%
  • MDL No.MFCD00085541

*For research and further manufacturing use only, not for direct human use.

Ethyl 3-(benzylamino)propanoate|CS-W015263

Structure of 23583-21-3

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General Information

  • CAS No. 23583-21-3
  • Cat. No. CS-W015263
  • Purity ≥97%
  • MDL No. MFCD00085541
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇NO₂
  • Molecular Weight 207.27
  • Synonym(s) N-Benzyl-β-alanine Ethyl Ester
  • SMILES O=C(OCC)CCNCC1=CC=CC=C1

Description

Ethyl 3-(benzylamino)propanoate features a benzylamino group conjugated to a propanoate ester, enabling seamless integration into peptide-like scaffolds. This bench-stable intermediate facilitates efficient coupling reactions and serves as a key building block in medicinal chemistry for accessing bioactive amine-containing compounds.

Application

Ethyl 3-(benzylamino)propanoate serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles and amino acid derivatives. Its benzylamine functionality supports orthogonal protection strategies, while the ester group facilitates selective transformations under standard conditions. The compound exhibits excellent bench stability and ease of purification, making it well-suited for multi-step synthesis workflows.

Synthesis

  • Route1
    • null|null
      100-46-9
    • null|null
      140-88-5
    • ~95%
    • In-stock
      Ethyl 3-(benzylamino)propanoate|CS-W015263
      23583-21-3

    References

    • Xu, Li-Wen; Li, Jing-Wei; Xia, Chun-Gu; Zhou, Shao-Lin; Hu, Xiao-Xue Synlett, 2003 , # 15 p. 2425 - 2427
  • Route2
    • null|null
      100-46-9
    • null|null
      140-88-5
    • ~%
    • In-stock
      Ethyl 3-(benzylamino)propanoate|CS-W015263
      23583-21-3
    • Diethyl 3,3'-(benzylazanediyl)dipropionate|CS-0331337
      6938-07-4

    References

    • Journal of the American Chemical Society, , vol. 69, p. 971
  • Route3
    • In-stock
      Ethyl 3-bromopropanoate|CS-W007449
      539-74-2
    • null|null
      100-46-9
    • ~77%
    • In-stock
      Ethyl 3-(benzylamino)propanoate|CS-W015263
      23583-21-3

    References

    • Gill; Freeman; Irwin; Wilson European Journal of Medicinal Chemistry, 1996 , vol. 31, # 11 p. 847 - 859

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.7294
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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