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(S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid Vildagliptin Impurity

  • CAS No. 23500-10-9

  • Cat. No. CS-0165391
  • Purity≥97%
  • MDL No.MFCD00046089

*For research and further manufacturing use only, not for direct human use.

(S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid  Vildagliptin Impurity|CS-0165391

Structure of 23500-10-9

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General Information

  • CAS No. 23500-10-9
  • Cat. No. CS-0165391
  • Purity ≥97%
  • MDL No. MFCD00046089
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀ClNO₃
  • Molecular Weight 191.61
  • Synonym(s) (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxylic acid
  • SMILES O=C([C@H]1N(C(CCl)=O)CCC1)O

Synthesis

  • Route1
    • null|null
      79-04-9
    • L-Proline Enalapril  Impurity|CS-0229432
      147-85-3
    • ~96%
    • (S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid  Vildagliptin Impurity|CS-0165391
      23500-10-9

    References

    • Peng, Jun; Feng, Yue; Tao, Zhu; Chen, Yingjie; Hu, Xiangnan Letters in Organic Chemistry, 2013 , vol. 10, # 3 p. 159 - 163
  • Route2
    • null|null
      79-11-8
    • L-Proline Enalapril  Impurity|CS-0229432
      147-85-3
    • ~%
    • (S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylic acid  Vildagliptin Impurity|CS-0165391
      23500-10-9

    References

    • Fedorov; Shestopalov; Belyakov Russian Chemical Bulletin, 2003 , vol. 52, # 10 p. 2197 - 2202
  • Route3

    References

    • Hamer; Greenstein Journal of Biological Chemistry, 1951 , vol. 193, p. 81,87

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   57.61
  • LogP   0.3008
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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