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CS-W001157 4
Total: USD 88.00

[(1S,2R)-rel-2-(hydroxymethyl)cyclopropyl]methanol

  • CAS No. 2345-68-8

  • Cat. No. CS-0053077
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

[(1S,2R)-rel-2-(hydroxymethyl)cyclopropyl]methanol|CS-0053077

Structure of 2345-68-8

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General Information

  • CAS No. 2345-68-8
  • Cat. No. CS-0053077
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O₂
  • Molecular Weight 102.13
  • Synonym(s) rel-(1R,2S)-Cyclopropane-1,2-diyldimethanol
  • SMILES OC[C@H]1C[C@H]1CO

Description

This cyclopropylmethanol derivative features a stereodefined hydroxymethyl group enabling precise structural integration in chiral synthesis. The rigid cyclopropyl scaffold imparts conformational stability, while the primary alcohol facilitates derivatization under standard conditions. Ideal for medicinal chemistry and natural product synthesis workflows.

Application

[(1S,2R)-rel-2-(hydroxymethyl)cyclopropyl]methanol serves as a valuable chiral building block for the synthesis of cyclopropyl-containing pharmaceuticals and bioactive molecules. Its rigid cyclopropane core imparts conformational constraint, while the two distinct hydroxyl groups enable selective derivatization and protection strategies. The molecule demonstrates excellent bench stability and compatibility with standard organic transformations, facilitating efficient access to complex heterocyclic scaffolds and drug-like intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.3929
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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