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CS-W001157 4
Total: USD 88.00

tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate

  • CAS No. 234082-33-8

  • Cat. No. CS-0151755
  • Purity≥98%
  • MDL No.MFCD09031688

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate|CS-0151755

Structure of 234082-33-8

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General Information

  • CAS No. 234082-33-8
  • Cat. No. CS-0151755
  • Purity ≥98%
  • MDL No. MFCD09031688
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₆N₂O₄
  • Molecular Weight 334.41
  • Synonym(s) Ethyl 4-(4-BOC-piperazino)benzoate
  • SMILES CCOC(=O)C1=CC=C(C=C1)N2CCN(CC2)C(=O)OC(C)(C)C

Synthesis

  • Route1
    • In-stock
      Ethyl 4-fluorobenzoate|CS-W017810
      451-46-7
    • N-Boc-piperazine Olaparib Impurity|CS-0214004
      57260-71-6
    • ~58%
    • In-stock
      tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate|CS-0151755
      234082-33-8

    References

    • THERAVANCE, INC. Patent: US2012/114600 A1, 2012 ;
  • Route2
    • null|null
      123-91-1
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • ~%
    • In-stock
      tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate|CS-0151755
      234082-33-8

    References

    • Meiji Seika Kaisha, Ltd. Patent: US6451800 B1, 2002 ;
  • Route3

    References

    • Kubota, Dai; Ishikawa, Minoru; Yamamoto, Mikio; Murakami, Shoichi; Hachisu, Mitsugu; Katano, Kiyoaki; Ajito, Keiichi Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 7 p. 2089 - 2108

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P261-P280-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   59.08
  • LogP   2.9204
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   3

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