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Structure of 23386-40-5
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1-Oxoisoindoline-5-carboxylic acid features a rigid, electron-deficient isoindoline core paired with a carboxylic acid group, enabling direct incorporation into diverse synthetic scaffolds. This bench-stable, moisture-tolerant building block integrates efficiently in medicinal chemistry campaigns targeting kinase inhibitors and bioactive heterocycles.
1-Oxoisoindoline-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of isoindoline-based scaffolds prevalent in bioactive molecules. Its carboxylic acid functionality facilitates direct amidation, esterification, and coupling reactions, while the conjugated ketone group supports electrophilic transformations and metal-catalyzed cross-couplings. The molecule exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: