Lot numbers can be found on the outside label of a product:
(1S,2R)-2-Amino-1,2-diphenylethanol
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CAS No. 23364-44-5
- Cat. No. CS-M0824
- Purity≥97%
- MDL No.MFCD00074959
*For research and further manufacturing use only, not for direct human use.
Structure of 23364-44-5
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General Information
- CAS No. 23364-44-5
- Cat. No. CS-M0824
- Purity ≥97%
- MDL No. MFCD00074959
- Storage 4°C, protect from light, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₄H₁₅NO
- Molecular Weight 213.28
- Synonym(s) None
- SMILES N[C@@H]([C@H](C1=CC=CC=C1)O)C2=CC=CC=C2
Description
(1S,2R)-(+)-2-Amino-1,2-diphenylethanol can be used:To prepare vanadium(V) Schiff base complexes, which are used as catalysts in the oxidation of sulfides and olefins.To prepare chiral selectors, which are immobilized on aminated silica gel, applicable as chiral stationary phase in HPLC.To immobilize on the frame of -zirconium phosphate to yield layered zirconium phosphonates, which are used in the heterogeneous catalysis.As a chiral auxiliary in the preparation of homopropargylic alcohols from aliphatic and aromatic aldehydes.
Application
(1S,2R)-2-Amino-1,2-diphenylethanol serves as a chiral building block for the synthesis of biologically active compounds, offering high stereochemical fidelity and bench stability. Its pendant amine and hydroxyl groups enable orthogonal functionalization, facilitating downstream derivatization in medicinal chemistry. The molecule exhibits excellent compatibility with standard coupling and protection protocols, making it a reliable scaffold for heterocycle construction and peptide-like motif integration.
Synthesis
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Route1
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In-stock
441-38-3 - ~66%
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In-stock
23364-44-5
References
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Davis, Franklin A.; Haque, M. S.; Przeslawski, Robert M. Journal of Organic Chemistry, 1989 , vol. 54, # 8 p. 2021 - 2024
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Route2
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620141-05-1 - ~82%
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In-stock
23364-44-5
References
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Garcia Ruano, Jose L.; Aleman, Jose Organic Letters, 2003 , vol. 5, # 23 p. 4513 - 4516
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Route3
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184674-48-4
- ~81%
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In-stock
23364-44-5
References
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Huang, Meng-Ting; Wu, Hsin-Yi; Chein, Rong-Jie Chemical Communications, 2014 , vol. 50, # 9 p. 1101 - 1103
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 46.25
- LogP 2.42
- H_Acceptors 2
- H_Donors 2
- Rotatable_Bonds 3
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Key Words
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