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(R)-1,2,3,4-Tetrahydronaphthalen-1-ol

  • CAS No. 23357-45-1

  • Cat. No. CS-0079970
  • Purity≥97%
  • MDL No.MFCD00063005

*For research and further manufacturing use only, not for direct human use.

(R)-1,2,3,4-Tetrahydronaphthalen-1-ol|CS-0079970

Structure of 23357-45-1

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General Information

  • CAS No. 23357-45-1
  • Cat. No. CS-0079970
  • Purity ≥97%
  • MDL No. MFCD00063005
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O
  • Molecular Weight 148.20
  • Synonym(s) (R)-(-)-α-Tetralol
  • SMILES O[C@@H]1CCCC2=C1C=CC=C2

Description

(R)-1,2,3,4-Tetrahydronaphthalen-1-ol is a chiral intermediate featuring a rigid tetralin scaffold with a stereodefined hydroxyl group. This bench-stable alcohol enables selective functionalization in asymmetric synthesis, serving as a key building block for complex natural product and pharmaceutical candidates.

Synthesis

  • Route1

    References

    • Sarvary, Ian; Almqvist, Fredrik; Frejd, Torbjoern Chemistry - A European Journal, 2001 , vol. 7, # 10 p. 2158 - 2166
  • Route2

    References

    • Doucet, Henri; Fernandez, Elena; Layzell, Timothy P.; Brown, John M. Chemistry - A European Journal, 1999 , vol. 5, # 4 p. 1320 - 1330
  • Route3
    • null|null
      23357-51-9
    • ~47%
    • null|null
      65915-64-2
    • In-stock
      (R)-1,2,3,4-Tetrahydronaphthalen-1-ol|CS-0079970
      23357-45-1

    References

    • Tetrahedron Asymmetry, , vol. 23, # 11-12 p. 828 - 833

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.0563
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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