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CS-W001157 4
Total: USD 88.00

2-Bromo-4-methyl-1H-imidazole

  • CAS No. 23328-88-3

  • Cat. No. CS-W020387
  • Purity≥95%
  • MDL No.MFCD22123438

*For research and further manufacturing use only, not for direct human use.

2-Bromo-4-methyl-1H-imidazole|CS-W020387

Structure of 23328-88-3

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General Information

  • CAS No. 23328-88-3
  • Cat. No. CS-W020387
  • Purity ≥95%
  • MDL No. MFCD22123438
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₅BrN₂
  • Molecular Weight 161.00
  • Synonym(s) 2-bromo-5-methyl-1h-imidazole
  • SMILES CC1=CNC(Br)=N1

Description

2-Bromo-4-methyl-1H-imidazole is a bench-stable heterocyclic building block featuring a bromine substituent at the 2-position and a methyl group at the 4-position, enabling direct functionalization in cross-coupling reactions. The imidazole core provides strong coordination potential and enhanced solubility in polar solvents, facilitating use in synthetic medicinal chemistry and catalytic system development.

Application

2-Bromo-4-methyl-1H-imidazole serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C2 position via palladium-catalyzed cross-coupling reactions. Its stability under standard synthetic conditions and tolerance to common functional groups facilitate efficient access to substituted imidazoles. The methyl group enhances regioselectivity in downstream transformations, making it particularly valuable for constructing bioactive heterocyclic scaffolds in drug discovery workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   1.48062
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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