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CS-W001157 4
Total: USD 88.00

3-(methylthio)propyl methanesulfonate

  • CAS No. 232944-38-6

  • Cat. No. CS-M0564
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(methylthio)propyl methanesulfonate|CS-M0564

Structure of 232944-38-6

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General Information

  • CAS No. 232944-38-6
  • Cat. No. CS-M0564
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂O₃S₂
  • Molecular Weight 184.28
  • Synonym(s) 3-(Methylthio)propyl methanesulfonate
  • SMILES O=S(OCCCSC)(C)=O

Description

3-(methylthio)propyl (methanesulfonate) is a reactive sulfide electrophile featuring a labile methanesulfonate leaving group. This bifunctional moiety enables efficient conjugation strategies in synthetic chemistry, particularly in the installation of thioether linkages under mild conditions. The methylthio substituent enhances lipophilicity and stability during handling, making it well-suited for use in probe design and bioconjugation workflows.

Application

3-(Methylthio)propyl (methanesulfonate) serves as a versatile alkylating agent in synthetic organic chemistry, enabling efficient introduction of the 3-(methylthio)propyl moiety into nucleophilic substrates. Its methanesulfonate leaving group ensures high reactivity under mild conditions, with good stability and ease of handling. This reagent facilitates C–S bond formation and is particularly useful in the synthesis of thioether-containing building blocks for medicinal chemistry and functional materials.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   43.37
  • LogP   0.7157
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   5

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