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CS-W001157 4
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Methyl 2-hydroxy-3-methylbenzoate

  • CAS No. 23287-26-5

  • Cat. No. CS-0153704
  • Purity≥97%
  • MDL No.MFCD00020051

*For research and further manufacturing use only, not for direct human use.

Methyl 2-hydroxy-3-methylbenzoate|CS-0153704

Structure of 23287-26-5

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General Information

  • CAS No. 23287-26-5
  • Cat. No. CS-0153704
  • Purity ≥97%
  • MDL No. MFCD00020051
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃
  • Molecular Weight None
  • Synonym(s) Methyl o-Cresotinate
  • SMILES CC1=C(C(=CC=C1)C(=O)OC)O

Description

Propargyl-PEG1-SS-PEG1-propargyl is a homoebifunctional cleavable PEG linker containing two propargyl groups and a disulfide bond. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. Disulfide bond cn be cleaved with reducing agent.

Synthesis

  • Route1
    • In-stock
      3-Methylsalicylic acid|CS-4909
      83-40-9
    • null|null
      77-78-1
    • ~87%
    • In-stock
      Methyl 2-hydroxy-3-methylbenzoate|CS-0153704
      23287-26-5

    References

    • Rasapalli, Sivappa; Jarugumilli, Gopalakrishna; Yarrapothu, Gangadhara Rao; Golen, James A.; Rheingold, Arnold L. Tetrahedron Letters, 2013 , vol. 54, # 21 p. 2615 - 2618
  • Route2
    • null|null
      67-56-1
    • In-stock
      3-Methylsalicylic acid|CS-4909
      83-40-9
    • ~95%
    • In-stock
      Methyl 2-hydroxy-3-methylbenzoate|CS-0153704
      23287-26-5

    References

    • Dean, Melissa A.; Hitchcock, Shawn R. Tetrahedron Asymmetry, 2010 , vol. 21, # 20 p. 2471 - 2478
  • Route3

    References

    • Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 2 p. 155 - 160

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.48722
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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