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CS-W001157 4
Total: USD 88.00

3-(Pyridin-2-yl)-1,2,4-triazole

  • CAS No. 23195-62-2

  • Cat. No. CS-0012683
  • Purity≥95%
  • MDL No.MFCD13188589

*For research and further manufacturing use only, not for direct human use.

3-(Pyridin-2-yl)-1,2,4-triazole|CS-0012683

Structure of 23195-62-2

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General Information

  • CAS No. 23195-62-2
  • Cat. No. CS-0012683
  • Purity ≥95%
  • MDL No. MFCD13188589
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆N₄
  • Molecular Weight 146.15
  • Synonym(s) None
  • SMILES N=1N=C(NC1)C=2N=CC=CC2

Application

3-(Pyridin-2-yl)-1,2,4-triazole serves as a versatile heterocyclic building block in medicinal chemistry and catalyst design. Its pyridine-triazole fusion enables strong coordination to transition metals and facilitates hydrogen bonding in target binding. The compound exhibits excellent bench stability, broad functional group tolerance, and compatibility with standard coupling reactions. It functions as a key scaffold in the synthesis of kinase inhibitors and metal-ligand complexes, offering predictable reactivity in both solution-phase and solid-phase workflows.

Synthesis

  • Route1
    • In-stock
      2-Cyanopyridine|CS-W020084
      100-70-9
    • null|null
      624-84-0
    • ~9%
    • In-stock
      3-(Pyridin-2-yl)-1,2,4-triazole|CS-0012683
      23195-62-2

    References

    • Howard, Steven; Amin, Nader; Benowitz, Andrew B.; Chiarparin, Elisabetta; Cui, Haifeng; Deng, Xiaodong; Heightman, Tom D.; Holmes, David J.; Hopkins, Anna; Huang, Jianzhong; Jin, Qi; Kreatsoulas, Constantine; Martin, Agnes C. L.; Massey, Frances; McCloskey, Lynn; Mortenson, Paul N.; Pathuri, Puja; Tisi, Dominic; Williams, Pamela A. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 12 p. 1208 - 1212
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 47, # 19 p. 4645 - 4648
  • Route3

    References

    • US5635485 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   54.46
  • LogP   0.8667
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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